The main exacerbation of the pain in migraine is the enlargement of the head and brain vessels with the effect of the trigeminovascular system on the vessels. Migraine headaches can see in children.
However, after the effects of hormones in adolescence and stress factors. Come into play, the frequency, and severity of pain between the ages of 35-45 effect daily life. Predisposed to hypersensitivity of the nerve.
Botulinum toxin is a drug that has found its place as the gold standard treatment in many different fields since 1989 and was approved by the FDA in 2009. Specifically for the mechanism of the formation of chronic migraine.
The effectiveness and safety of the drug have been documented by thousands of studies and patients.
There is very clear scientific evidence for its use in migraines. Botulinum toxin significantly increases the number of pain-free days in chronic migraine patients and enables patients to return to daily life with an increase in their quality of life.
VACCINE METHOD IN MIGRAINE TREATMENT
Attack treatments that is, the drugs used during a migraine attack are not suitable for long-term use. The first of these is the triptan group drugs that we know to be effective.
These drugs cannot be used more than 6-8 tablets per month. Botulinum toxin is the only approved treatment option for chronic migraine.
Safe treatment in patients with frequent attacks of 15 days or more.
Increasing interest in many diseases that could not be cured in the past can now be treated with the biological medicine revolution.
However, prioritized for the use of life-threatening diseases due to research. Development processes and production costs.
The drug defined as migraine vaccine (erenumab) is in the biological drug group and is basically not a vaccine.
There is no such thing as completely treating and ending migraines. Because it is an injectable product, it has taken this name among the people.
This drug blocks the receptors on the vessel to which cgrp substance. Released from the trigeminal nerve endings. Causes the vessels to dilate.
HOW IS THE VACCINE Administered?
Erenumab approved by the FDA for migraine preventive (prophylaxis) use. In patients with monthly headache days between 4 and 15.
Injection once a month reduced the number of migraine headache days by 50% in approximately 40% of the patients in the 3rd month.
Specially developed for migraines in cases such as lifestyle changes. Insufficiency of acute treatments.
However, the balance between monthly treatment costs. Evaluated by a specialist neurologist.
Nerve blockades are also among the economical options for patients who cannot benefit enough from conventional drugs in the treatment of migraines.
Botulinum toxin is the most effective and safe drug. Today for patients with more than 3 migraine attacks per month.
8 days of migraine pain, and 15 or more days with headache.
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